History, Mission and Vision
The Center for Reproductive Medicine was founded in 1993 as the research program of the Glickman Urological & Kidney Institute, Cleveland Clinic . Our research fellowship, ART training and summer mentorship opportunities represent one of the largest and most comprehensive academic programs of its kind in the United States. We are continuously striving to enhance the quality of our research and training, based on feedback received from every research fellow and trainee who participates in our programs. We believe that our willingness to listen and make changes in our Center has helped us create one of the finest research programs in the world.

The Cleveland Clinic Center for Reproductive Medicine’s mission is to conduct cutting-edge research into the causes of human reproductive and sexual disorders, leading to the development of new treatments and cures, as well as training of physicians and scientists to advance the understanding of human reproduction, infertility and sexual function.

The Cleveland Clinic Center for Reproductive Medicine’s vision is to mentor and train each research fellow, trainee and summer intern using an individualized approach, to develop technical expertise and the ability to work independently.
Click to view accreditationThe Cleveland Clinic Center for Reproductive Medicine is accredited by the American College of Embryology.
The Cleveland Clinic Andrology Laboratory and Reproductive Tissue Bank is fully accredited by the College of American Pathologists' Reproductive Laboratory Accreditation Program.

The Cleveland Clinic Andrology Laboratory and Reproductive Tissue Bank is accredited for Recovery, Processing, Storage, and Distribution of Reproductive Tissue for Transplantation by the American Association of Tissue Banks.
Certificate of Recognition
Scholarship in Teaching Award 2013 Training Program in Advanced Reproductive Techniques

The Case Western Reserve School of Medicine Scholarship in Teaching Awards is an annual program designed to recognize faculty contribution to education from the preceding year and promote undergraduate, graduate, and continuing medical education teaching as a scholarly activity.

Teaching approaches considered scholarly are characterized by 1) purposeful planning 2) systematic implementation and 3) reflection and assessment for improvement. The result should be an academic product that is actively shared and that will support the development of a community of teaching scholars.

This award was given out at the Case Medical School Education Retreat on March 6, 2014.
Research @ CRM

The Center for Reproductive Medicine conducts basic science and clinical research into oxidative stress, proteomics and male infertility.

For an up to date list of our publications, kindly visit Dr. Agarwal’s Research Gate Profile.

A Web of Science Citation Report of Research Publications by the Center for Reproductive Medicine from 1993 to 2013 is available here.

Director, Center of Reproductive Medicine
Ashok Agarwal, PhD, HCLD (ABB), EMB (ACE)
Research Coordinator, Center of Reproductive Medicine
Rakesh Sharma, PhD
Supervisor, Andrology Center and Reproductive Tissue Bank
Sajal Gupta, MBBS, MS, TS (ABB)
Invited Trainers, Clinical Embryologist
Certificates & Testimonials
Israel Maldonado Ross, MS


Training Program in Assisted Reproductive Techniques (ART)
Duration:40 hours (1 week)
Fees:USD 5,295.00
Course:Routine Semen Analysis
Duration:8 hours (1 day)
Fees:USD 950.00

Course:Sperm Morphology
Duration:16 hours (2 days)
Fees:USD 1,395.00
Course:Advanced Andrology Techniques
Duration:32 hours (4 days)
Fees:USD 4,750.00

Course:ART Sperm Preparation
Duration:16 hours (2 days)
Fees:USD 2,250.00
Course:Cryopreservation Techniques
Duration:8 hours (1 day)
Fees:USD 1,950.00

Course:IVF / ICSI / Micromanipulation
Duration:80 hours (2 weeks)
Fees:USD 7,950.00
Course:ICSI / Micromanipulation
Duration:40 hours (1 week)
Fees:USD 6,200.00

Course:Advanced ART Techniques
Duration:40 hours (1 week)
Fees:USD 6,850.00
Course:Customized ART Training
Duration:Selected by Trainee
Fees:To Be Determined

Duration:8 hours (1 day)
Fees:USD 2,500.00
Course:Management of IVF and Andrology Labs
Duration:16 hours (2 days)
Fees:USD 2,800.00

Course:Preparing for CAP and AATB Accreditation
Duration:16 hours (2 days)
Fees:USD 2,800.00
General Course Objectives:
  • Acquire a basic understanding of assisted reproductive techniques
  • Acquire the skills in the use of a micromanipulator
  • Impact hands-on training in intracytoplasmic sperm injection
  • Acquire skills in various assisted reproductive procedures
  • Observe aspiration and retrieval of oocytes
  • Participate actively in interactive sessions/lectures
Specific Course Objectives:
  • Click on each course name to learn its specific objectives
General Teaching and Learning Methods:
  1. Fully hands-on, one-to-one laboratory training sessions will be provided under the direct tutelage of 2 highly-competent and practising Clinical Embryologists
    * Module 5 involves training using animal models (frozen hamster oocyte and mouse embryos)
  2. Other Trainers include Andrologists, Reproductive Endocrinologists and other invited ART experts
  3. Each training session is customized to the Trainee's
    1. Professional background
    2. Level of skill and competence
    3. Specific training needs
    4. Desired outcomes obtained from attending the ART training course
  4. Interactive discussion and teaching sessions
  5. Live lectures and multimedia presentations in small group sessions
  6. Four state-of-the-art micromanipulators dedicated solely for training purposes (IVF/ICSI)
Course Syllabus
  • Click on each module to view a sample course syllabus
Assessment Methods

Aspects of the Training that will be assessed include:

  1. Knowledge: There will be a summative test comprising multiple choice questions on the practical and theoretical aspects of the ART for each module
  2. Practical Skills: Each Trainee will be individually tested for competency on specific laboratory techniques learnt during the module
  3. Presentation and Communication Skills: Each Trainee will be required to give a talk (oral with and without the aid of slides) during the course of the module

Scholarship in Teaching Award
This Training Program in Advanced Reproductive Techniques has been recognized by a Scholarship in Teaching Award in 2013 by the Case Western Reserve School of Medicine
What Each Trainee Will Receive
  1. Course Syllabus with Reading Material and Lab Protocols
  2. Free Access to the Cleveland Clinic Alumni Library
  3. Free Text Book on “Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices” edited by Dr. Peter Nagy et al, Springer
  4. WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. 5th Edition (CD)
  5. Certificate of Training (issued upon successful assessment by the instructor)
  6. Daily Meal Tickets
Training Certificate
A Certificate of Training will be issued upon successful assessment of competency by the Trainers
Course Evaluation by Past Trainees

Click here to learn more about the evaluation of our training modules by our Past Trainees

Testimonials by Past Trainee

Click here to learn more about what our Past Trainees have to say about their training experience

Application Procedure

Information regarding the application procedure is available here.

Online Application Form

Online application forms are available here.

Contact the Course Director

Drop us a line, the Course Director would love to hear from you!

Ashok Agarwal, PhD, HCLD
Program Director
Assisted Reproduction Training (ART)
Center for Reproductive Medicine
Cleveland Clinic
10681 Carnegie Avenue, X11
Cleveland, OH 44195, USA
Tel: (216) 444-9485
Fax: (216) 445-6049
E-mail: crm@ccf.org

Clinicians, biologists, scientists and other health professionals with a background and interest in the field of Embryology, Gynecology, Reproductive Medicine, and Andrology are encouraged to apply. Both national and international candidates are welcomed.
International Applicants
International candidates are encouraged to apply. For specific requirements that may apply to your country, please write to the Program Director, Dr Ashok Agarwal crm@ccf.org. Details on past International candidates who have successfully completed the Center for Reproductive Medicine's Assisted Reproduction Training (ART) training program are available here.
When you apply, we will need to know about your highest academic degree, your specialty, your training objectives, your previous experience in the related area, and your training interests in order to customize your training program.

The following documents are required for your application:
  • Recent curriculum vitae/resume
  • A letter of recommendation from advisors, teachers, or persons who have first-hand knowledge of you. The following is not acceptable: LORs sent as an e-mail and not printed on official letterhead, not carrying a signature, letters written more than 6-8 weeks before the date of submission.
  • Passport size picture
  • Copy of passport
Courses are typically held every year during the Fall months (September and October) Those who require training in March or outside these months are requested to reach out to the Program Director, Dr Ashok Agarwal via: crm@ccf.org.
Application Opens:Application Closes:
November 1 of every yearJune 15 of every year
English Language
The medium of instruction throughout the training program is in English. Candidates should ideally be able to converse in English with minimum difficulty in order to follow through with the training, assessments and presentations.
The current module training fee structure is available here.

The training fee  must be submitted as a money order or certified bank check (no personal checks) made payable to "Andrology Lab Research Program." This course fee should be mailed by courier (UPS or FedEx) upon acceptance to the program. Fees must be paid in full, 8 weeks in advance by a Certified Bank Check made out to the "Andrology Lab Research Program".

Please mail your check to:
Program Director
Center for Reproductive Medicine &
Andrology Laboratory
Glickman Urological & Kidney Institute
The Cleveland Clinic
10681 Carnegie Ave., X11
Cleveland, Ohio 44195, USA

Candidates can submit training fee by electronic wire transfer from their bank. Please contact the Program Director for details of our bank account in Cleveland Clinic. Candidates choosing bank transfer for payment of their training fee will be charged $50 by our Center to cover the money deducted by the bank during the transfer of funds.

Please note that there is no discount for multiple training modules (eg. Modules 1, 2, 3 = USD11,150.00 and will last 2 weeks).

Request for refunds of 50% of course fees may be allowed if requests are received in writing up to 4 weeks prior to the scheduled training. No refunds will be issued if made after that time.

A non-refundable document fee of USD $200 is required in the form of a money order or certified bank check - payable to "Cleveland Clinic Foundation."  This fee is required for candidates applying from outside the United States.  The fee is charged by Cleveland Clinic's Center for International Medical Education for their appointment of foreign-based candidates.

Ready to Apply?
Kindly note that all required fields in the online application form must be completed and attachments must be submitted together at the time of application.

Forward any questions about the course requirements or application process to:

Ashok Agarwal, PhD, HCLD
Program Director
Assisted Reproduction Training (ART) Center for Reproductive Medicine
Cleveland Clinic
10681 Carnegie Avenue, X11
Cleveland, OH 44195, USA
Tel: (216) 444-9485
Fax: (216) 445-6049
E-mail: crm@ccf.org.

Andrology Center
The Laboratories
The Research and Clinical Laboratories occupy over 5000 square feet of workspace with state-of-the-art instruments and facilities for advanced research in fertility preservation in patients with cancer, proteomics of male and female infertility and molecular markers of oxidative stress and DNA integrity.
Research Laboratories
Equipment and Instrumentation
Instruments available in our facility include: computer assisted semen analyzers, luminometer for oxidative stress measurements, Accuri BD C6 flow cytometer, equipment for western blot, culture room equipped with a sterile hood, several incubators, microscopes, and Narishige micromanipulator fitted on an inverted phase-contrast microscope, spectrophotometers, ELISA plate reader, centrifuges, liquid nitrogen storage tanks, programmable freezers, cold room, etc.
Alumni Library
A large collection of scientific journals, electronic journals/books, and other databases are available through the resourceful Cleveland Clinic Alumni Library.

Specialized Medical Librarians are ever willing to help in research and use of electronic databases.

Alumni Library Online
Alumni Community/Network
Course Evaluation
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Dr. Agarwal's Biosketch Citation Metrics 20 years of CRM Research Global Author Ranking Books Published
Cleveland, Ohio  

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For an up to date list of our publications, kindly visit https://www.researchgate.net/profile/Ashok_Agarwal2/. A Web of Science Citation Report of Research Publications by the Center for Reproductive Medicine from 1993 to 2013 is available here.

Visitors Upto since October 2001 Last Update: January 22, 2014