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800.223.2273 Ext. 49485
Andrology Lab appointments:
800.223.2273 Ext 48182 or 216.444.8182

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Male Infertility


Infertility is a common problem, with more than 5 million couples in the United States dealing with these problems. Infertility affects one in every six couples who are trying to conceive. In at least half of all cases of infertility, a male factor is a major or contributing cause. This means that about 10% of all men in the United States who are attempting to conceive suffer from infertility. Click here to watch a short video on Male Infertility produced by the American Society for Reproductive Medicine.

The Andrology Laboratory and Reproductive Tissue Bank at The Cleveland Clinic Foundation provides patients various services including diagnostic testing and therapeutic sperm banking. Men undergoing cancer treatment, including some type of chemotherapy, radiation therapy or surgery, face the possibility of temporary or permanent damage to their fertility. Physicians know which treatments are likely to cause a problem, but often cannot predict how severely a man's fertility may be affected by his cancer treatment, or for how long. An option to preserve a man's potential to father his own children at some future time is to freeze, or cryopreserve, samples of sperm before cancer treatment begins. This process is called therapeutic sperm banking.

Therapeutic sperm banking is also available to men who are going to have a vasectomy, allowing them the chance to conceive a child in the future. Occasionally, therapeutic sperm banking is recommended in other situations when a man's fertility could be damaged by surgery, medical treatments or exposure to a toxic environment. If you are not sure whether a medical treatment could damage your fertility, please discuss the issue with your physician.

Our center also provides specialized tests and services to evaluate male infertility and help couples who are attempting to achieve a pregnancy. Our Laboratory offers referring physicians accurate, quantifiable results using the latest, most sophisticated technology available. Our personnel include only highly qualified and experienced laboratory technologists, all certified by the American Society of Clinical Pathologists. Our laboratory is CLIA certified by the Department of Health and Human Services and has received accreditation from the College of American Pathologists in conjunction with the American Society for Reproductive Medicine.

The laboratory tests offered include a comprehensive semen analysis using a computerized system which allows for the quality of the semen to be studied through multiple exposure videomicrography. Results are then analyzed by computerassisted semen analyzer or CASA. Other tests include: direct Immunobead testing to detect antisperm antibodies in sperm. Special stains can be utilized for the presence of sperm in azoospermic specimen. A post-vasectomy screen is available for those patients who have recently had a vasectomy.


For an up to date list of our publications, kindly visit A Web of Science Citation Report of Research Publications by the American Center for Reproductive Medicine from 1993 to 2013 is available here.